Dynamite News Know how novel immune cell therapy can fight hepatitis B infections
Researchers found out how chronic infection with the hepatitis B virus (HBV) causes gradual liver damage. Read further on Dynamite News:
Washington: Researchers found out how chronic infection with the hepatitis B virus (HBV) causes gradual liver damage, and eradicating the virus remains a daunting challenge.
According to new research published in FEBS Letters, therapy that amplifies the impact of immune cells known as stem cell memory T cells (TSCMs) could be a promising technique for treating HBV.
In the study, investigators identified TSCMs in patients with chronic HBV infection and analyzed their effects in a mouse model of HBV.
Also Read |
Research shows early stages of HIV infection in human body
After introducing TSCMs from patients into the mice, the immune cells differentiated into cytotoxic T cells and activated a strong response that resulted in the elimination of HBV-infected liver cells.
Therefore, augmenting patients' TSCMs may help the immune system overcome the virus.
"Our hepatitis model may reveal how TSCMs differentiate into cytotoxic T cells and uncover the fate of differentiated T cells.
Also Read |
Researchers find new method that help overcome resistance treatment in cancer
Such information could greatly advance future research on T cell-based therapies," said corresponding author Hiromi Abe-Chayama, PhD, of Hiroshima University, in Japan.